Respiratory infections are extremely common pediatric illnesses, and families frequently treat children with cough and cold medicines (CCM). In 2008, the US Food and Drug Administration (FDA) recommended that children younger than 2 years not use over-the-counter (OTC) CCM given concerns about efficacy and safety.1 Soon thereafter, manufacturers voluntarily relabeled CCM for children 4 years and older,1 and the American Academy of Pediatrics recommended avoiding CCM in children younger than 6 years. Subsequent national US utilization studies through 2010 showed equivocal effects on pediatric CCM use.2,3 We studied trends over a broader timeframe in physicians’ recommendations for CCM and, for comparison, antihistamines in the US pediatric population. Read more